Professor

Laboratory

Publications

Board

Publications National Leading Research Laboratory of Molecular Modeling & Drug Design

Journals

  • Publications
  • Journals
  • 97
    Discovery and Biological Evaluation of N-Methyl-pyrrolo[2,3-b]pyridine-5-carboxamide Derivatives as JAK1-Selective Inhibitors

    Eunsun Park†, Sun Joo Lee†, Heegyum Moon, Jongmi Park, Hyeonho Jeon, Ji Sun Hwang, Hayoung Hwang, Ki Bum Hong, Seung-Hee Han, Sun Choi, and Soosung Kang*

    Journal of Medicinal Chemistry, 2021, 64(2), 958-979. (SCIE, IF 7.446, ’20)

    Link
  • 96
    Discovery of Benzopyridone-Based Transient Receptor Potential Vanilloid 1 Agonists and Antagonists and the Structural Elucidation of Their Activity Shift

    Shivaji A. Thorat†, Yoonji Lee†, Aeran Jung, Jihyae Ann, Songyeon Ahn, Jisoo Baek, Dongxu Zuo, Nayeon Do, Jin Ju Jeong, Peter M. Blumberg, Timothy E. Esch, Noe A. Turcios, Larry V. Pearce, Hee-Jin Ha, Young Dong Yoo, Sunhye Hong, Sun Choi*, and Jeewoo Lee*

    Journal of Medicinal Chemistry, 2021, 64(1), 370-384. (SCIE, IF 7.446, ’20)

    Link
  • 95
    Advances in Molecular Dynamics Simulations and Enhanced Sampling Methods for the Study of Protein Systems

    Raudah Lazim†, Donghyuk Suh†, and Sun Choi*

    International Journal of Molecular Sciences, 2020, 21(17), 6339. (SCIE, IF 4.556, ’19)

    Link
  • 94
    Asymmetric Total Syntheses of Kopsane Alkaloids via a PtCl2‐Catalyzed Intramolecular [3+2] Cycloaddition

    Xuelei Jia, Honghui Lei, Feipeng Han, Tao Zhang, Ying Chen, Zhengshuang Xu, Pratanphorn Nakliang, Sun Choi, Yian Guo*, and Tao Ye*

    Angewandte Chemie-International Edition, 2020, 59(31), 12832-12836. (SCIE, IF 12.959, ’19)

    Link
  • 93
    Multiscale Molecular Modeling in G Protein-Coupled Receptor (GPCR)-Ligand Studies

    Pratanphorn Nakliang, Raudah Lazim, Hyerim Chang, and Sun Choi*

    Biomolecules, 2020, 10(4), 631. (SCIE, IF 4.082, ’19)

    Link
  • 92
    Discovery of Conformationally Restricted Human Glutaminyl Cyclase Inhibitors as Potent Anti-Alzheimer’s Agents by Structure-Based Design

    Van-Hai Hoang†, Van T H Ngo†, Minghua Cui†, Nguyen Van Manh, Phuong-Thao Tran, Jihyae Ann, Hee-Jin Ha, Hee Kim, Kwanghyun Choi, Young-Ho Kim, Hyerim Chang, Stephani Joy Y Macalino, Jiyoun Lee, Sun Choi*, and Jeewoo Lee*

    Journal of Medicinal Chemistry, 2019, 62(17), 8011-8027. (SCIE, IF 6.054, ’18)

    Link
  • 91
    Water-Soluble Phthalocyanines Selectively Bind to Albumin Dimers: A Green Approach Toward Enhancing Tumor-Targeted Photodynamic Therapy

    Xingshu Li†, Keunsoo Jeong†, Yoonji Lee†, Tian Guo, Dayoung Lee, Jeongmin Park, Nahyun Kwon, Jung-Hyun Na, Seung Kon Hong, Sun-Shin Cha, Jian-Dong Huang*, Sun Choi*, Sehoon Kim*, and Juyoung Yoon*

    Theranostics, 2019, 9(22), 6412-6423. (SCIE, IF 8.063, ’18)

    Link
  • 90
    Total Synthesis of Hoiamide A Using an Evans−Tishchenko Reaction as a Key Step

    Yian Guo, Jingjing Zhou, Bowen Gao, Meng Zhao, Jia-Lei Yan, Zhengshuang Xu, Sun Choi, and Tao Ye*

    Organic Letters, 2019, 21(14), 5471-5474. (SCIE, IF 6.555, ’18)

    Link
  • 89
    Transmembrane 4 L Six Family Member 5 Senses Arginine for mTORC1 Signaling

    Jae Woo Jung, Stephani Joy Y. Macalino, Minghua Cui, Ji Eon Kim, Hye-Jin Kim, Dae-Geun Song, Seo Hee Nam, Semi Kim, Sun Choi*, and Jung Weon Lee*

    Cell Metabolism, 2019, 29(6), 1306-1319. (SCIE, IF 22.415, ’18)

    Link
  • 88
    Importance of protein dynamics in the structure-based drug discovery of class A G protein-coupled receptors (GPCRs)

    Yoonji Lee, Raudah Lazim, Stephani Joy Y. Macalino, and Sun Choi*

    Current Opinion in Structural Biology, 2019, 55, 147-153. (SCIE, IF 7.052, ’18)

    Link
  • 87
    In Vivo Albumin Traps Photosensitizer Monomers from Self-Assembled Phthalocyanine Nanovesicles: A Facile and Switchable Theranostic Approach

    Xingshu Li, Sungsook Yu, Yoonji Lee, Tian Guo, Nahyun Kwon, Dayoung Lee, Su Cheong Yeom, Yejin Cho, Gyoungmi Kim, Jian-Dong Huang, Sun Choi*, Ki Taek Nam*, and Juyoung Yoon*

    Journal of the American Chemical Society, 2019, 141(3), 1366-1372. (SCIE, IF 14.695, ’18)

    Link
  • 86
    Integrated Ligand and Structure-Based Investigation of Structural Requirements for Silent Information Regulator 1 (SIRT1) Activation

    Amit K. Gupta and Sun Choi*

    Current Topics in Medicinal Chemistry, 2018, 18(27), 2313-2324. (SCIE, IF 3.374, ’17)

    Link
  • 85
    Adaptable Small Ligand of CYP1 Enzymes for Use in Understanding the Structural Features Determining Isoform Selectivity

    Joo-Youn Lee, Hyunkyung Cho, Sundarapandian Thangapandian, Chaemin Lim, Young-Jin Chun, Yoonji Lee, Sun Choi, and Sanghee Kim*

    ACS Medicinal Chemistry Letters, 2018, 9(12), 1247-1252. (SCIE, IF 3.794, ’17)

    Link
  • 84
    Structural and Biochemical Characterization of the Curcumin-Reducing Activity of CurA from Vibrio vulnificus

    Soo-Bong Park†, Da-Woon Bae†, Nina Abigail B. Clavio†, Lei Zhao, Chang-Sook Jeong, Bo Mee Choi, Stephani Joy Y. Macalino, Hee-Jeong Cha, Jin-Byung Park, Jun Hyuck Lee, Sang-Jip Nam, Sun Choi*, Min-Kyu Kim*, and Sun-Shin Cha*

    Journal of Agricultural and Food Chemistry, 2018, 66(40), 10608-10616. (SCIE, IF 3.412, ’17)

    Link
  • 83
    Evolution of In Silico Strategies for Protein-Protein Interaction Drug Discovery

    Stephani Joy Y. Macalino†, Shaherin Basith†, Nina Abigail B. Clavio, Hyerim Chang, Soosung Kang*, and Sun Choi*

    Molecules, 2018, 23(8), 1963. (SCIE, IF 3.098, ’17)

    Link
  • 82
    4-Aminophenyl acetamides and propanamides as potent transient receptor potential vanilloid 1 (TRPV1) ligands

    Changhoon Kim, Jihyae Ann, Sunho Lee, Eunhye Kim, Sun Choi, Peter M. aBlumberg, Robert Frank-Foltyn, Gregor Bahrenberg, Hannelore Stockhausen, Thomas Christoph, and Jeewoo Lee*

    Bioorganic & Medicinal Chemistry, 2018, 26(15), 4509-4517. (SCIE, IF 2.881, ’17)

    Link
  • 81
    Structure-activity relationship investigation of Phe-Arg mimetic region of human glutaminyl cyclase inhibitors

    Van T.H. Ngo, Van-Hai Hoang, Phuong-Thao Tran, Nguyen Van Manh, Jihyae Ann, Eunhye Kim, Minghua Cui, Sun Choi, Jiyoun Lee, Hee Kim, Hee-Jin Ha, Kwanghyun Choi, Young-Ho Kim, and Jeewoo Lee*

    Bioorganic & Medicinal Chemistry, 2018, 26(12), 3133-3144. (SCIE, IF 2.881, ’17)

    Link
  • 80
    Exploring G Protein-Coupled Receptors (GPCRs) Ligand Space via Cheminformatics Approaches: Impact on Rational Drug Design

    Shaherin Basith†, Minghua Cui†, Stephani Joy Y. Macalino, Jongmi Park, Nina Abigail B. Clavio, and Sun Choi*

    Frontiers in Pharmacology, 2018, 9, 128. (SCIE, IF 3.831, ’17)

    Link
  • 79
    Potent human glutaminyl cyclase inhibitors as potential anti-Alzheimer’s agents: Structure-activity relationship study of Arg-mimetic region

    Van T.H. Ngo, Van-Hai Hoang, Phuong-Thao Tran, Jihyae Ann, Minghua Cui, Gyungseo Park, Sun Choi, Jiyoun Lee, Hee Kim, Hee-Jin Ha, Kwanghyun Choi, Young-Ho Kim, and Jeewoo Lee*

    Bioorganic & Medicinal Chemistry, 2018, 26(5), 1035-1049. (SCIE, IF 2.881, ’17)

    Link
  • 78
    Understanding G Protein-Coupled Receptor Allostery via Molecular Dynamics Simulations: Implications for Drug Discovery

    Shaherin Basith, Yoonji Lee, and Sun Choi*

    Computational Drug Discovery and Design in Methods in Molecular Biology book series, 2018, 1762, 455-472.

    Link
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