Professor

Laboratory

Publications

Board

Publications National Leading Research Laboratory of Molecular Modeling & Drug Design

Journals

  • Publications
  • Journals
  • 120
    Unique molecular architecture of the large extracellular loop for N-glycosylated TM4SF5 dimer comparative of small four-transmembrane proteins

    Yoonji Lee*,†, Ji Eon Kim†, Wonsik Kim, Soyeon Kim, Ri Han, Donghyuk Suh, Eunmi Kim, Eun-Ae Shin, Kyung-hee Pyo, Jae-Ho Lee, Sanghee Yoon, Yong-In Kim, Je-Yoel Cho, Sun Choi*, and Jung Weon Lee*

    Journal of Advanced Research, 2025, In Press. (SCIE, IF 13.0, '24)

  • 119
    Employing Automated Machine Learning (AutoML) Methods to Facilitate the In Silico ADMET Properties Prediction

    Herim Han†, Bilal Shaker†, Jin Hee Lee†, Sunghwan Choi†, Sanghee Yoon†, Maninder Singh, Shaherin Basith, Minghua Cui, Sunil Ahn, Junyoung An, Soosung Kang, Min Sun Yeom*, and Sun Choi*

    Journal of Chemical Information and Modeling, 2025, 65(7), 3215-3225. (SCIE, IF 5.7, '23)

    Link
  • 118
    Exploring the Use of AI/ML Technologies in Medicinal Chemistry and Drug Discovery

    Sun Choi, Ashley M. Adams, and Kelly Chibale*

    ACS Medicinal Chemistry Letters, 2025, 16(2), 174. (SCIE, IF 4.0, '24)

    Link
  • 117
    The anticancer effect of Metformin targets VDAC1 via ER-mitochondria interaction-mediated autophagy in HCC

    Minjeong Ko†, Jiho Kim†, Raudah Lazim†, Ju Yeon Lee, Jin Young Kim, Vijayakumar Gosu, Yoonji Lee, Sun Choi*, and Ho Jeong Kwon*

    Experimental & Molecular Medicine, 2024, 56, 2714-2725. (SCIE, IF 12.9, '24)

    Link
  • 116
    GolpHCat (TMEM87A), a unique voltage-dependent cation channel in Golgi apparatus, contributes to Golgi-pH maintenance and hippocampus-dependent memory

    Hyunji Kang†, Ah-reum Han†, Aihua Zhang†, Heejin Jeong, Wuhyun Koh, Jung Moo Lee, Hayeon Lee, Hee Young Jo, Miguel A. Maria-Solano, Mridula Bhalla, Jea Kwon, Woo Suk Roh, Jimin Yang, Hyun Joo An, Sun Choi*, Ho Min Kim*, and C. Justin Lee*

    Nature Communications, 2024, 15, 5830. (SCIE, IF 14.7, '23)

    Link
  • 115
    Fc engineered anti-virus therapeutic human IgG1 expressed in plants with altered binding to the neonatal Fc receptor

    Sol-Ah Park†, Yoonji Lee†, Hyunjoo Hwang†, Jeong Hwan Lee, Yang Joo Kang, Yerin Kim, Caiquan Jin, Hyun Joo An, Yoo Jin Oh, Peter Hinterdorfer, Eunhye Kim, Sun Choi*, and  Kisung Ko*

    Biotechnology Journal, 2024, 19(3), e2300552. (SCIE, IF 3.2, ’23)

    Link
  • 114
    Glucose-mediated mitochondrial reprogramming by cholesterol export at TM4SF5-enriched mitochondria-lysosome contact siteds

    Ji Eon Kim, So-Young Park, Chulhwan Kwak, Yoonji Lee, Dae-Geun Song, Jae Woo Jung, Haesong Lee, Eun-Ae Shin, Yangie Pinanga, Kyung-hee Pyo, Eun Hae Lee, Wonsik Kim, Soyeon Kim, Chang-Duck Jun, Jeanho Yun, Sun Choi, Hyun-Woo Rhee, Kwang-Hyeon Liu*, and Jung Weon Lee*

    Cancer Communications, 2024, 44(1), 47-75. (SCIE, IF 20.1, ’23)

    Link
  • 113
    Dynamic allosteric networks drive adenosine A1 receptor activation and G-protein coupling

    Miguel A. Maria-Solano​* and Sun Choi​* 

    eLife, 2023, 12(3), 31a. (SCIE, IF 7.7, ’22)

    Link
  • 112
    DMAP and TBPP-Mediated Synthesis of Urea-Substituted Nucleobases and Nucleosides

    Chaebin Han, Sun Choi, and Jinha Yu* 

    Tetrahedron, 2023, 140, 133472. (SCIE, IF 2.1, ’22)

    Link
  • 111
    On the classical reaction rate and the first-time problems of Brownian motion

    Aihua Zhang​* and Sun Choi​* 

    Physica A: Statistical Mechanics and its Applications, 2023, 622, 128823. (SCIE, IF 3.3, ’22)

    Link
  • 110
    Albumin-binding photosensitizer capable of targeting glioma via the SPARC pathway

    Xingshu Li†, Jae Sang Oh†, Yoonji Lee†, Eun Chae Lee, Mengyao Yang, Nahyun Kwon, Tae Won Ha, Dong‑Yong Hong​ , Yena Song, Hyun Kyu Kim, Byung Hoo Song, Sun Choi*, Man Ryul Lee*, and Juyoung Yoon​*

    Biomaterials Research, 2023, 27(1), 23. (SCIE, IF 11.3, ’22)

    Link
  • 109
    Structure–Activity Relationships of Truncated 1′-Homologated Carbaadenosine Derivatives as New PPARγ/δ Ligands: A Study on Sugar Puckering Affecting Binding to PPARs

    Young Eum Hyun, Seungchan An, Minjae Kim, In Guk Park, Sanghee Yoon, Hafiz Muhammad Ahmad Javaid, Thi Ngoc Lan Vu, Gyudong Kim, Hongseok Choi, Hyuk Woo Lee, Minsoo Noh, Joo Young Huh, Sun Choi, Hong-Rae Kim, and Lak Shin Jeong*
    Journal of Medicinal Chemistry, 2023, 66(7), 4961-4978. (SCIE, IF 7.3, ’22)

    Link
  • 108
    Total synthesis of thioamycolamide A using diastereoselective sulfa-Michael addition as the key step

    Yi Xiao, Yangyang Jiang, Chao Xu, Pratanphorn Nakliang, Sanghee Yoon, Sun Choi*, Yian Guo*, and Tao Ye*  

    Organic Chemistry Frontiers, 2022, 9(15), 3998-4002. (SCIE, IF 5.456, ’21)

    Link
  • 107
    GPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches for the A2A Adenosine Receptor

    Anna Shiriaeva†, Daejin Park†, Gyudong Kim†, Yoonji Lee†, Xiyan Hou, Dnyandev B. Jarhad, Gibae Kim, Jinha Yu, Young Eum Hyun, Woomi Kim, Zhan-Guo Gao, Kenneth A. Jacobson, Gye Won Han, Raymond C. Stevens, Lak Shin Jeong*, Sun Choi*, and Vadim Cherezov*

    Journal of Medicinal Chemistry, 2022, 65 (17), 11648-11657. (SCIE, IF 8.039, ’21)

    Link
  • 106
    Discovery of (E)-3-(3-((2-Cyano-4' -dimethylaminobiphenyl-4-ylmethyl)cyclohexanecarbonylamino)-5-fluorophenyl)acrylic Acid Methyl Ester, an Intestine-Specific, FXR Partial Agonist for the Treatment of Nonalcoholic Steatohepatitis

    Soyeon Shim, Maddeboina Krishnaiah, Madhusudana Reddy Sankham, Inha Kim, Yoseob Lee, Irin Shin, A Reum Oh, Hwa Jeong Lee, Thi Ngoc Lan Vu, Jongmi Park, Sun Choi, Seojeong Park, Youngjoo Kwon, Sungsoon Fang*, and Dae-Kee Kim*

    Journal of Medicinal Chemistry, 2022, 65(14), 9974-10000. (SCIE, IF 8.039, ’21)

    Link
  • 105
    CHARMM-GUI Enhanced Sampler for various collective variables and enhanced sampling methods

    Donghyuk Suh, Shasha Feng, Hwayoung Lee, Han Zhang, Sang-Jun Park, Seonghan Kim, Jumin Lee, Sun Choi*, and Wonpil Im*

    Protein Science,  2022, 31(11), e444​6. (SCIE, IF 6.993, ’21)

    Link
  • 104
    Big data and artificial intelligence (AI) methodologies for computer-aided drug design (CADD)

    Jai Woo Lee, Miguel A Maria-Solano, Thi Ngoc Lan Vu, Sanghee Yoon, and Sun Choi*

    Biochemical Society Transactions, 2022, 50(1), 241-252. (SCIE, IF 4.919, ’21)

    Link
  • 103
    Subtle Chemical Changes Cross the Boundary between Agonist and Antagonist: New A3 Adenosine Receptor Homology Models and Structural Network Analysis Can Predict This Boundary

    Yoonji Lee, Xiyan Hou, Jin Hee Lee, Akshata Nayak, Varughese Alexander, Pankaz K. Sharma, Hyerim Chang, Khai Phan, Zhan-Guo Gao, Kenneth A. Jacobson, Sun Choi*, and Lak Shin Jeong*

    Journal of Medicinal Chemistry, 2021, 64(17), 12525-12536. (SCIE, IF 7.446, ’20)

    Link
  • 102
    2-(Halogenated Phenyl) acetamides and propanamides as potent TRPV1 antagonists

    Jin Mi Kang, Sun Ok Kwon, Jihyae Ann, Sunho Lee, Changhoon Kim, Nayeon Do, Jin Ju Jeong, Peter M.Blumberg, Heejin Ha, Thi Ngoc Lan Vu, Sanghee Yoon, Sun Choi, Robert Frank-Foltyn, Bernhard Lesch, Gregor Bahrenberg, Hannelore Stockhausen, Thomas Christoph, and Jeewoo Lee*

    Bioorganic & Medicinal Chemistry Letters, 2021, 48, 128266. (SCIE, IF 2.823, ’20)

    Link
  • 101
    N-terminus-independent activation of c-Src via binding to a tetraspan(in) TM4SF5 in hepatocellular carcinoma is abolished by the TM4SF5 C-terminal peptide application

    Haeng Eun Song†, Yoonji Lee†, Eunmi Kim†, Chang Yun Cho, Oisun Jung, Doohyung Lee, Eun Goo Lee, Seo Hee Nam, Minkyung Kang, Stephani Joy Y. Macalino, Ji Eon Kim, Jae Woo Jung, Sung Won Kwon, Sun Choi*, and Jung Weon Lee*

    Theranostics, 2021, 11(16), 8092-8111. (SCIE, IF 11.556, ’20)

    Link
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