Professor

Laboratory

Publications

Board

Publications National Leading Research Laboratory of Molecular Modeling & Drug Design

Journals

  • Publications
  • Journals
  • 95
    Advances in Molecular Dynamics Simulations and Enhanced Sampling Methods for the Study of Protein Systems

    Raudah Lazim†, Donghyuk Suh†, and Sun Choi*

    International Journal of Molecular Sciences, 2020, 21(17), 6339. (SCIE, IF 4.556, ’19)

    Link
  • 94
    Asymmetric Total Syntheses of Kopsane Alkaloids via a PtCl2‐Catalyzed Intramolecular [3+2] Cycloaddition

    Xuelei Jia, Honghui Lei, Feipeng Han, Tao Zhang, Ying Chen, Zhengshuang Xu, Pratanphorn Nakliang, Sun Choi, Yian Guo*, and Tao Ye*

    Angewandte Chemie-International Edition, 2020, 59(31), 12832-12836. (SCIE, IF 12.959, ’19)

    Link
  • 93
    Multiscale Molecular Modeling in G Protein-Coupled Receptor (GPCR)-Ligand Studies

    Pratanphorn Nakliang, Raudah Lazim, Hyerim Chang, and Sun Choi*

    Biomolecules, 2020, 10(4), 631. (SCIE, IF 4.082, ’19)

    Link
  • 92
    Discovery of Conformationally Restricted Human Glutaminyl Cyclase Inhibitors as Potent Anti-Alzheimer’s Agents by Structure-Based Design

    Van-Hai Hoang†, Van T H Ngo†, Minghua Cui†, Nguyen Van Manh, Phuong-Thao Tran, Jihyae Ann, Hee-Jin Ha, Hee Kim, Kwanghyun Choi, Young-Ho Kim, Hyerim Chang, Stephani Joy Y Macalino, Jiyoun Lee, Sun Choi*, and Jeewoo Lee*

    Journal of Medicinal Chemistry, 2019, 62(17), 8011-8027. (SCIE, IF 6.054, ’18)

    Link
  • 91
    Water-Soluble Phthalocyanines Selectively Bind to Albumin Dimers: A Green Approach Toward Enhancing Tumor-Targeted Photodynamic Therapy

    Xingshu Li†, Keunsoo Jeong†, Yoonji Lee†, Tian Guo, Dayoung Lee, Jeongmin Park, Nahyun Kwon, Jung-Hyun Na, Seung Kon Hong, Sun-Shin Cha, Jian-Dong Huang*, Sun Choi*, Sehoon Kim*, and Juyoung Yoon*

    Theranostics, 2019, 9(22), 6412-6423. (SCIE, IF 8.063, ’18)

    Link
  • 90
    Total Synthesis of Hoiamide A Using an Evans−Tishchenko Reaction as a Key Step

    Yian Guo, Jingjing Zhou, Bowen Gao, Meng Zhao, Jia-Lei Yan, Zhengshuang Xu, Sun Choi, and Tao Ye*

    Organic Letters, 2019, 21(14), 5471-5474. (SCIE, IF 6.555, ’18)

    Link
  • 89
    Transmembrane 4 L Six Family Member 5 Senses Arginine for mTORC1 Signaling

    Jae Woo Jung, Stephani Joy Y. Macalino, Minghua Cui, Ji Eon Kim, Hye-Jin Kim, Dae-Geun Song, Seo Hee Nam, Semi Kim, Sun Choi*, and Jung Weon Lee*

    Cell Metabolism, 2019, 29(6), 1306-1319. (SCIE, IF 22.415, ’18)

    Link
  • 88
    Importance of protein dynamics in the structure-based drug discovery of class A G protein-coupled receptors (GPCRs)

    Yoonji Lee, Raudah Lazim, Stephani Joy Y. Macalino, and Sun Choi*

    Current Opinion in Structural Biology, 2019, 55, 147-153. (SCIE, IF 7.052, ’18)

    Link
  • 87
    In Vivo Albumin Traps Photosensitizer Monomers from Self-Assembled Phthalocyanine Nanovesicles: A Facile and Switchable Theranostic Approach

    Xingshu Li, Sungsook Yu, Yoonji Lee, Tian Guo, Nahyun Kwon, Dayoung Lee, Su Cheong Yeom, Yejin Cho, Gyoungmi Kim, Jian-Dong Huang, Sun Choi*, Ki Taek Nam*, and Juyoung Yoon*

    Journal of the American Chemical Society, 2019, 141(3), 1366-1372. (SCIE, IF 14.695, ’18)

    Link
  • 86
    Integrated Ligand and Structure-Based Investigation of Structural Requirements for Silent Information Regulator 1 (SIRT1) Activation

    Amit K. Gupta and Sun Choi*

    Current Topics in Medicinal Chemistry, 2018, 18(27), 2313-2324. (SCIE, IF 3.374, ’17)

    Link
  • 85
    Adaptable Small Ligand of CYP1 Enzymes for Use in Understanding the Structural Features Determining Isoform Selectivity

    Joo-Youn Lee, Hyunkyung Cho, Sundarapandian Thangapandian, Chaemin Lim, Young-Jin Chun, Yoonji Lee, Sun Choi, and Sanghee Kim*

    ACS Medicinal Chemistry Letters, 2018, 9(12), 1247-1252. (SCIE, IF 3.794, ’17)

    Link
  • 84
    Structural and Biochemical Characterization of the Curcumin-Reducing Activity of CurA from Vibrio vulnificus

    Soo-Bong Park†, Da-Woon Bae†, Nina Abigail B. Clavio†, Lei Zhao, Chang-Sook Jeong, Bo Mee Choi, Stephani Joy Y. Macalino, Hee-Jeong Cha, Jin-Byung Park, Jun Hyuck Lee, Sang-Jip Nam, Sun Choi*, Min-Kyu Kim*, and Sun-Shin Cha*

    Journal of Agricultural and Food Chemistry, 2018, 66(40), 10608-10616. (SCIE, IF 3.412, ’17)

    Link
  • 83
    Evolution of In Silico Strategies for Protein-Protein Interaction Drug Discovery

    Stephani Joy Y. Macalino†, Shaherin Basith†, Nina Abigail B. Clavio, Hyerim Chang, Soosung Kang*, and Sun Choi*

    Molecules, 2018, 23(8), 1963. (SCIE, IF 3.098, ’17)

    Link
  • 82
    4-Aminophenyl acetamides and propanamides as potent transient receptor potential vanilloid 1 (TRPV1) ligands

    Changhoon Kim, Jihyae Ann, Sunho Lee, Eunhye Kim, Sun Choi, Peter M. aBlumberg, Robert Frank-Foltyn, Gregor Bahrenberg, Hannelore Stockhausen, Thomas Christoph, and Jeewoo Lee*

    Bioorganic & Medicinal Chemistry, 2018, 26(15), 4509-4517. (SCIE, IF 2.881, ’17)

    Link
  • 81
    Structure-activity relationship investigation of Phe-Arg mimetic region of human glutaminyl cyclase inhibitors

    Van T.H. Ngo, Van-Hai Hoang, Phuong-Thao Tran, Nguyen Van Manh, Jihyae Ann, Eunhye Kim, Minghua Cui, Sun Choi, Jiyoun Lee, Hee Kim, Hee-Jin Ha, Kwanghyun Choi, Young-Ho Kim, and Jeewoo Lee*

    Bioorganic & Medicinal Chemistry, 2018, 26(12), 3133-3144. (SCIE, IF 2.881, ’17)

    Link
  • 80
    Exploring G Protein-Coupled Receptors (GPCRs) Ligand Space via Cheminformatics Approaches: Impact on Rational Drug Design

    Shaherin Basith†, Minghua Cui†, Stephani Joy Y. Macalino, Jongmi Park, Nina Abigail B. Clavio, and Sun Choi*

    Frontiers in Pharmacology, 2018, 9, 128. (SCIE, IF 3.831, ’17)

    Link
  • 79
    Potent human glutaminyl cyclase inhibitors as potential anti-Alzheimer’s agents: Structure-activity relationship study of Arg-mimetic region

    Van T.H. Ngo, Van-Hai Hoang, Phuong-Thao Tran, Jihyae Ann, Minghua Cui, Gyungseo Park, Sun Choi, Jiyoun Lee, Hee Kim, Hee-Jin Ha, Kwanghyun Choi, Young-Ho Kim, and Jeewoo Lee*

    Bioorganic & Medicinal Chemistry, 2018, 26(5), 1035-1049. (SCIE, IF 2.881, ’17)

    Link
  • 78
    Understanding G Protein-Coupled Receptor Allostery via Molecular Dynamics Simulations: Implications for Drug Discovery

    Shaherin Basith, Yoonji Lee, and Sun Choi*

    Computational Drug Discovery and Design in Methods in Molecular Biology book series, 2018, 1762, 455-472.

    Link
  • 77
    Inhibitory effect of tartrate against phosphate-induced DJ-1 aggregation

    Min Soo Kim, Sangmin Lee, Sanguk Yun, Pann-Ghill Suh, Jongmi Park, Minghua Cui, Sun Choi, Sun-Shin Cha*, and Wook Jin*

    International Journal of Biological Macromolecules, 2018, 107(Pt B), 1650-1658. (SCIE, IF 3.909, ’17)

    Link
  • 76
    Recent Advances in Structure-Based Drug Design Targeting Class A G Protein-Coupled Receptors Utilizing Crystal Structures and Computational Simulations

    Yoonji Lee†, Shaherin Basith†, and Sun Choi*

    Journal of Medicinal Chemistry, 2018, 61(1), 1-46. (SCIE, IF 6.253, ’17)

    Link
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