Professor

Laboratory

Publications

Board

Publications National Leading Research Laboratory of Molecular Modeling & Drug Design

Journals

  • Publications
  • Journals
  • 35
    Selectivity Enhancement Arising from Interactions at the PI3K Unique Pocket

    Yujeong Jeong, Junghyun Lee, Yoonji Lee, Kyungrok Ham, Sun Choi*, and Sungwoo Hong*

    ChemMedChem, 2012, 7(8), 1379-1383. (SCIE, IF 3.151, ’11) 

    Link
  • 34
    Structural Origins for the Loss of Catalytic Activities of Bifunctional Human LTA4H Revealed through Molecular Dynamics Simulations

    Sundarapandian Thangapandian, Shalini John, Prettina Lazar, Sun Choi, and Keun Woo Lee*

    PLoS One, 2012, 7(7), e41063. (SCIE, IF 4.092, ’11) 

    Link
  • 33
    8-Hydroxy-2-deoxyguanosine prevents plaque formation and inhibits vascular smooth muscle cell activation through Rac1 inactivation

    Joo Young Huh, Dong Ju Son, Yoonji Lee, Junghyun Lee, Boyeon Kim, Hwan Myung Lee, Hanjoong Jo, Sun Choi*, Hunjoo Ha*, and Myung-Hee Chung

    Free Radical Biology and Medicine, 2012, 53(1), 109-121. (SCIE, IF 5.423, ’11) 

    Link
  • 32
    Structure–activity relationships and molecular modeling of the N-(3-pivaloyloxy-2-benzylpropyl)-N'-[4-(methylsulfonylamino)benzyl] thiourea template for TRPV1 antagonism

    Rahul S. Bhondwe, Dong Wook Kang, Myeong Seop Kim, Ho Shin Kim, Seul-gi Park, Karam Son, Sun Choi, Krystle A. Lang Kuhs, Vladimir A. Pavlyukovets, Larry V. Pearce, Peter M. Blumberg, and Jeewoo Lee*

    Bioorganic & Medicinal Chemistry Letters, 2012, 22(11), 3656–3660. (SCIE, IF 2.554, ’11) 

    Link
  • 31
    Structure-Activity Relationships of Truncated C2- or C8-Substituted Adenosine Derivatives as Dual Acting A2A and A3 Adenosine Receptor Ligands

    Xiyan Hou, Mahesh S. Majik, Kyunglim Kim, Yuna Pyee, Yoonji Lee, Varughese Alexander, Hwa-Jin Chung, Hyuk Woo Lee, Girish Chandra, Jin Hee Lee, Seul-gi Park, Won Jun Choi, Hea Ok Kim, Khai Phan, Zhan-Guo Gao, Kenneth A. Jacobson, Sun Choi, Sang Kook Lee, and Lak Shin Jeong*

    Journal of Medicinal Chemistry, 2012, 55(1), 342−356. (SCIE, IF 5.248, ’11) 

    Link
  • 30
    N-4-t-Butylbenzyl 2-(4-methylsulfonylaminophenyl) propanamide TRPV1 antagonists: Structure–activity relationships in the A-region

    Yong Soo Kim, Min-Jung Kil, Sang-Uk Kang, HyungChul Ryu, Myeong Seop Kim, Yongsung Cho, Rahul S. Bhondwe, Shivaji A. Thorat, Wei Sun, Keliang Liu, Jin Hee Lee, Sun Choi, Larry V. Pearce, Vladimir A. Pavlyukovets, Matthew A. Morgan, Richard Tran, Jozsef Lazar, Peter M. Blumberg, and Jeewoo Lee*

    Bioorganic & Medicinal Chemistry, 2012, 20(1), 215-224. (SCIE, IF 2.921, ’11)

    Link
  • 29
    Link between allosteric signal transduction and functional dynamics in a multi-subunit enzyme: S-adenosylhomocysteine hydrolase

    Yoonji Lee, Lak Shin Jeong, Sun Choi*, and Changbong Hyeon*

    Journal of the American Chemical Society, 2011, 133(49), 19807-19815. (SCIE, IF 9.023, ’10) 

    Link
  • 28
    Structural insights into transient receptor potential vanilloid type 1 (TRPV1) from homology modeling, flexible docking, and mutational studies

    Jin Hee Lee, Yoonji Lee, HyungChul Ryu, Dong Wook Kang, Jeewoo Lee, Jozsef Lazar, Larry V. Pearce, Vladimir A. Pavlyukovets, Peter M. Blumberg, and Sun Choi*

    Journal of Computer-Aided Molecular Design, 2011, 25(4), 317–327. (SCIE, IF 3.374, ’10) 

    Link
  • 27
    trans-Stilbenoids: potent and selective inhibitors for human cytochrome P450 1B1

    Young-Jin Chun, Chaemin Lim, Seul Ong Ohk, Ji Min Lee, Jin Hee Lee, Sun Choi, and Sanghee Kim*

    MedChemComm, 2011, 2(5), 402-405. (SCIE, IF 2.800, ’11) 

    Link
  • 26
    Novel Oxidative Modifications in Redox-Active Cysteine Residues

    Jaeho Jeong, Yongsik Jung, Seungjin Na, Jihye Jeong, Eunsun Lee, Mi-Sun Kim, Sun Choi, Dong-Hae Shin, Eunok Paek, Hee-Yoon Lee*, and Kong-Joo Lee*

    Molecular & Cellular Proteomics, 2011, 10(3), M110 000513. (SCIE, IF 8.354, ’10)

    Link
  • 25
    X-ray Crystal Structure and Binding Mode Analysis of Human S-Adenosylhomocysteine Hydrolase Complexed with Novel Mechanism-Based Inhibitors, Haloneplanocin A Analogues

    Kang Man Lee, Won Jun Choi, Yoonji Lee, Hyun Joo Lee, Long Xuan Zhao, Hyuk Woo Lee, Jae Gyu Park, Hea Ok Kim, Kwang Yeon Hwang, Yong-Seok Heo, Sun Choi*, and Lak Shin Jeong*

    Journal of Medicinal Chemistry, 2011, 54(4), 930-938. (SCIE, IF 5.207, ’10)

    Link
  • 24
    Receptor activity and conformational analysis of 5'-halogenated resiniferatoxin analogs as TRPV1 ligands

    Kwang Su Lim, Dong Wook Kang, Yong Soo Kim, Myeong Seop Kim, Seul-gi Park, Sun Choi, Larry V. Pearce, Peter M. Blumberg, and Jeewoo Lee*

    Bioorganic & Medicinal Chemistry Letters, 2011, 21(1), 299-302. (SCIE, IF 2.661, ’10) 

    Link
  • 23
    Design, synthesis, and binding of homologated truncated 4'-thioadenosine derivatives at the human A3 adenosine receptors

    Hyuk Woo Lee, Hea Ok Kim, Won Jun Choi, Sun Choi, Jin Hee Lee, Seul-gi Park, Lena Yoo, Kenneth A. Jacobson, and Lak Shin Jeong*

    Bioorganic & Medicinal Chemistry, 2010, 18(19), 7015-7021. (SCIE, IF 2.822, ’09) 

    Link
  • 22
    Discovery of A New Human A2A Adenosine Receptor Agonist, Truncated2-Hexynyl-4´-thioadenosine

    Xiyan Hou, Hea Ok Kim, Varughese Alexander, Kyunglim Kim, Sun Choi, Seul-gi Park, Jin Hee Lee, Lena S. Yoo, Zhan-Guo Gao, Kenneth A. Jacobson, and Lak Shin Jeong* 

    ACS Medicinal Chemistry Letters, 2010, 1(9), 516-520. (SCIE, IF 3.355, '11)

    Link
  • 21
    Identification of a potent and noncytotoxic inhibitor of melanin production

    Soonho Hwang, Sang Yoon Choi, Jin Hee Lee, Shinae Kim, Jinkyung In, Sang Keun Ha, Eunjung Lee, Tae-Yoon Kim, Sun Yeou Kim, Sun Choi, and Sanghee Kim*

    Bioorganic & Medicinal Chemistry, 2010, 18(15), 5602-5609. (SCIE, IF 2.822, ’09)

    Link
  • 20
    In silico classification of adenosine receptor antagonists using Laplacian-modified naïve Bayesian, support vector machine, and recursive partitioning

    Jin Hee Lee, Sunkyung Lee, and Sun Choi*

    Journal of Molecular Graphics & Modelling, 2010, 28(8), 883–890. (SCIE, IF 2.169, ’09)

    Link
  • 19
    Herbal Compound Farnesiferol C Exerts Antiangiogenic and Antitumor Activity and Targets Multiple Aspects of VEGFR1 (Flt1) or VEGFR2 (Flk1) Signaling Cascades

    Jae-Ho Lee†, Sun Choi†, Yoonji Lee, Hyo-Jeong Lee, Kwan-Hyun Kim, Kyoo-Seok Ahn, Hyunsoo Bae, Hyo-Jung Lee, Eun-Ok Lee, Kwang-Seok Ahn, Shi Yong Ryu, Junxuan Lu, and Sung-Hoon Kim*

    Molecular Cancer Therapeutics, 2010, 9(2), 389-399. (SCIE, IF 4.953, ’09) 

    Link
  • 18
    Oxidative modifications of glyceraldehyde-3-phosphate dehydrogenase play a key role in its multiple cellular functions

    Na Rae Hwang, Seung-Hee Yim, Young Mee Kim, Jaeho Jeong, Eun Joo Song, Yoonji Lee, Jin Hee Lee, Sun Choi, and Kong-Joo Lee*

    Biochemical Journal, 2009, 423(2), 253-264. (SCIE, IF 4.371, ’08)

    Link
  • 17
    Discovery of a New Template for Anticancer Agents: 2´-deoxy-2´-fluoro-4´-selenoarabinofuranosyl-cytosine (2´-F-4´-Seleno-ara-C)

    Lak Shin Jeong, Dilip K. Tosh, Won Jun Choi, Sang Kook Lee, You-Jin Kang, Sun Choi, Jin Hee Lee, Hankil Lee, Hyuk Woo Lee, and Hea Ok Kim*

    Journal of Medicinal Chemistry, 2009, 52(17), 5303-5306. (SCIE, IF 4.898, ’08)

    Link
  • 16
    3D-QSAR Studies of Cytotoxic Heterocyclic Quinones Using Calculated Reduction Potential

    Yoonji Lee, Seoeun Kim, Hee-Kyung Rhee, Kyung-Eun Doh, Junhee Park, Chong-Ock Lee, Sun Choi*, and Hea-Young Park Choo* 

    Drug Development Research, 2009, 70(6), 438-444. (SCIE, IF 1.375, ’08)

    Link
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