Professor

Laboratory

Publications

Board

Publications National Leading Research Laboratory of Molecular Modeling & Drug Design

Journals

  • Publications
  • Journals
  • 7
    2‑(3-Fluoro-4-methylsulfonylaminophenyl) Propanamides as Potent Transient Receptor Potential Vanilloid 1 (TRPV1) Antagonists: Structure−Activity Relationships of 2‑Amino Derivatives in the N‑(6-Trifluoromethylpyridin-3-ylmethyl) C‑Region

    Myeong Seop Kim, HyungChul Ryu, Dong Wook Kang, Seong-Hee Cho, Sejin Seo, Young Soo Park, Mi-Yeon Kim, Eun Joo Kwak, Yong Soo Kim, Rahul S. Bhondwe, Ho Shin Kim, Seul-gi Park, Karam Son, Sun Choi, Ian A. DeAndrea-Lazarus, Larry V. Pearce, Peter M. Blumberg, Robert Frank, Gregor Bahrenberg, Hannelore Stockhausen, Babette Y. Kögel, Klaus Schiene, Thomas Christoph, and Jeewoo Lee*

    Journal of Medicinal Chemistry, 2012, 55(19), 8392-8408. (SCIE, IF 5.248, ’11) 

    Link
  • 6
    Selectivity Enhancement Arising from Interactions at the PI3K Unique Pocket

    Yujeong Jeong, Junghyun Lee, Yoonji Lee, Kyungrok Ham, Sun Choi*, and Sungwoo Hong*

    ChemMedChem, 2012, 7(8), 1379-1383. (SCIE, IF 3.151, ’11) 

    Link
  • 5
    Structural Origins for the Loss of Catalytic Activities of Bifunctional Human LTA4H Revealed through Molecular Dynamics Simulations

    Sundarapandian Thangapandian, Shalini John, Prettina Lazar, Sun Choi, and Keun Woo Lee*

    PLoS One, 2012, 7(7), e41063. (SCIE, IF 4.092, ’11) 

    Link
  • 4
    8-Hydroxy-2-deoxyguanosine prevents plaque formation and inhibits vascular smooth muscle cell activation through Rac1 inactivation

    Joo Young Huh, Dong Ju Son, Yoonji Lee, Junghyun Lee, Boyeon Kim, Hwan Myung Lee, Hanjoong Jo, Sun Choi*, Hunjoo Ha*, and Myung-Hee Chung

    Free Radical Biology and Medicine, 2012, 53(1), 109-121. (SCIE, IF 5.423, ’11) 

    Link
  • 3
    Structure–activity relationships and molecular modeling of the N-(3-pivaloyloxy-2-benzylpropyl)-N'-[4-(methylsulfonylamino)benzyl] thiourea template for TRPV1 antagonism

    Rahul S. Bhondwe, Dong Wook Kang, Myeong Seop Kim, Ho Shin Kim, Seul-gi Park, Karam Son, Sun Choi, Krystle A. Lang Kuhs, Vladimir A. Pavlyukovets, Larry V. Pearce, Peter M. Blumberg, and Jeewoo Lee*

    Bioorganic & Medicinal Chemistry Letters, 2012, 22(11), 3656–3660. (SCIE, IF 2.554, ’11) 

    Link
  • 2
    Structure-Activity Relationships of Truncated C2- or C8-Substituted Adenosine Derivatives as Dual Acting A2A and A3 Adenosine Receptor Ligands

    Xiyan Hou, Mahesh S. Majik, Kyunglim Kim, Yuna Pyee, Yoonji Lee, Varughese Alexander, Hwa-Jin Chung, Hyuk Woo Lee, Girish Chandra, Jin Hee Lee, Seul-gi Park, Won Jun Choi, Hea Ok Kim, Khai Phan, Zhan-Guo Gao, Kenneth A. Jacobson, Sun Choi, Sang Kook Lee, and Lak Shin Jeong*

    Journal of Medicinal Chemistry, 2012, 55(1), 342−356. (SCIE, IF 5.248, ’11) 

    Link
  • 1
    N-4-t-Butylbenzyl 2-(4-methylsulfonylaminophenyl) propanamide TRPV1 antagonists: Structure–activity relationships in the A-region

    Yong Soo Kim, Min-Jung Kil, Sang-Uk Kang, HyungChul Ryu, Myeong Seop Kim, Yongsung Cho, Rahul S. Bhondwe, Shivaji A. Thorat, Wei Sun, Keliang Liu, Jin Hee Lee, Sun Choi, Larry V. Pearce, Vladimir A. Pavlyukovets, Matthew A. Morgan, Richard Tran, Jozsef Lazar, Peter M. Blumberg, and Jeewoo Lee*

    Bioorganic & Medicinal Chemistry, 2012, 20(1), 215-224. (SCIE, IF 2.921, ’11)

    Link
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