Professor

Laboratory

Publications

Board

Publications National Leading Research Laboratory of Molecular Modeling & Drug Design

Journals

  • Publications
  • Journals
  • 77
    Inhibitory effect of tartrate against phosphate-induced DJ-1 aggregation

    Min Soo Kim, Sangmin Lee, Sanguk Yun, Pann-Ghill Suh, Jongmi Park, Minghua Cui, Sun Choi, Sun-Shin Cha*, and Wook Jin*

    International Journal of Biological Macromolecules, 2018, 107(Pt B), 1650-1658. (SCIE, IF 3.909, ’17)

    Link
  • 76
    Recent Advances in Structure-Based Drug Design Targeting Class A G Protein-Coupled Receptors Utilizing Crystal Structures and Computational Simulations

    Yoonji Lee†, Shaherin Basith†, and Sun Choi*

    Journal of Medicinal Chemistry, 2018, 61(1), 1-46. (SCIE, IF 6.253, ’17)

    Link
  • 75
    In silico prediction of multiple-category classification model for cytochrome P450 inhibitors and non-inhibitors using machine-learning method

    Jin Hee Lee†, Shaherin Basith†, MingHui Cui, Bo youn Kim, and Sun Choi*

    SAR and QSAR in Environmental Research, 2017, 28(10), 863-874. (SCIE, IF 1.642, ’16)

    Link
  • 74
    MLACP: machine-learning-based prediction of anticancer peptides

    Balachandran Manavalan, Shaherin Basith, Tae Hwan Shin, Sun Choi, Myeong Ok Kim, and Gwang Lee*

    Oncotarget, 2017, 8(44), 77121-77136. (SCIE, IF 5.168, ’16)

    Link
  • 73
    Pyrazole C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as potent TRPV1 antagonists

    Sunho Lee, Changhoon Kim, Jihyae Ann, Shivaji A. Thorat, Eunhye Kim, Jongmi Park, Sun Choi, Peter M. Blumberg, Robert Frank-Foltyn, Gregor Bahrenberg, Hannelore Stockhausen, Thomas Christoph, and Jeewoo Lee*

    Bioorganic & Medicinal Chemistry Letters, 2017, 27(18), 4383-4388. (SCIE, IF 2.454, ’16)

    Link
  • 72
    N6‑Substituted 5′‑N‑Methylcarbamoyl-4′-selenoadenosines as Potent and Selective A3 Adenosine Receptor Agonists with Unusual Sugar Puckering and Nucleobase Orientation

    Jinha Yu, Long Xuan Zhao, Jongmi Park, Hyuk Woo Lee, Pramod K. Sahu, Minghua Cui, Steven M. Moss, Eva Hammes, Eugene Warnick, Zhan-Guo Gao, Minsoo Noh, Sun Choi, Hee-Chul Ahn, Jungwon Choi, Kenneth A. Jacobson, and Lak Shin Jeong*

    Journal of Medicinal Chemistry, 2017, 60(8), 3422-3437. (SCIE, IF 6.259, ’16) 

    Link
  • 71
    t-Butyl pyridine and phenyl C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as potent TRPV1 an atagonists

    Sunho Lee, Dong Wook Kang, HyunChul Ryu, Changhoon Kim, Jihyae Ann, Hobin Lee, Eunhye Kim, Sunhye Hong, Sun Choi, Peter M. Blumberg, Robert Frank-Foltyn, Gregor Bahrenberg, Hannelore Stockhausen, Thomas Christoph, and Jeewoo Lee*

    Bioorganic & Medicinal Chemistry, 2017, 25(8), 2451-2462. (SCIE, IF 2.930, ’16)

    Link
  • 70
    Discovery of Potent Human Glutaminyl Cyclase Inhibitors as Anti-Alzheimer’s Agents Based on Rational Design

    Van-Hai Hoang, Phuong-Thao Tran, Minghua Cui, Van T. H. Ngo, Jihyae Ann, Jongmi Park, Jiyoun Lee, Kwanghyun Choi, Hanyang Cho, Hee Kim, Hee-Jin Ha, Hyun-Seok Hong, Sun Choi, Young-Ho Kim, and Jeewoo Lee*

    Journal of Medicinal Chemistry, 2017, 60(6), 2573-2590. (SCIE, IF 6.259, ’16)

    Link
  • 69
    The discovery of 2,5-isomers of triazole-pyrrolopyrimidine as selective Janus kinase 2 (JAK2) inhibitors versus JAK1 and JAK3

    Sun-Mi Lee, Kyoung Bin Yoon, Hyo Jeong Lee, Jiwon Kim, You Kyoung Chung, Won-Jea Cho, Chisato Mukai, Sun Choi, Keon Wook Kang, Sun-Young Han*, Hyojin Ko*, and Yong-Chul Kim*

    Bioorganic & Medicinal Chemistry, 2016, 24(21), 5036-5046. (SCIE, IF 2.923, ’15)

    Link
  • 68
    Ultraslow Water-Mediated Transmembrane Interactions Regulate the Activation of A2A Adenosine Receptor

    Yoonji Lee, Songmi Kim, Sun Choi*, and Changbong Hyeon*

    Biophysical Journal, 2016, 111(6), 1180-1191. (SCIE, IF 3.632, ’15)

    Link
  • 67
    Synthesis and biological evaluation of 3-substituted 5-benzylidene-1-methyl-2-thiohydantoins as potent NADPH oxidase (NOX) inhibitors

    Yun Soo Bae†, Sun Choi†, Jung Jae Park, Jung Hee Joo, Minghua Cui, Hyunsung Cho, Won Jae Lee, and Sang Hyup Lee*

    Bioorganic & Medicinal Chemistry, 2016, 24(18), 4144-4151. (SCIE, IF 2.923, ’15)

    Link
  • 66
    Design, synthesis, and anticancer activity of C8-substituted-4’-thionucleosides as potential HSP90 inhibitors

    Shuhao Qu, Varughese A. Mulamoottil, Akshata Nayak, Seungyeon Ryu, Xiyan Hou, Jayoung Song, Jinha Yu, Pramod K. Sahu, Long Xuan Zhao, Sun Choi, Sang Kook Lee, and Lak Shin Jeong*

    Bioorganic & Medicinal Chemistry, 2016, 24(16), 3418-3428. (SCIE, IF 2.923, ’15)

    Link
  • 65
    Harnessing the Therapeutic Potential of Capsaicin and Its Analogues in Pain and Other Diseases

    Shaherin Basith, Minghua Cui, Sunhye Hong, and Sun Choi*

    Molecules, 2016, 21(8), 966. (SCIE, IF 2.465, ’15)

    Link
  • 64
    Discovery of N-(3-fluoro-4-methylsulfonamidomethylphenyl)urea as a potent TRPV1 antagonistic template

    Jihyae Ann, Wei Sun, Xing Zhou, Aeran Jung, Jisoo Baek, Sunho Lee, Changhoon Kim, Suyoung Yoon, Sunhye Hong, Sun Choi, Noe A. Turcios, Brienna K. A. Herold, Timothy E. Esch, Nancy E. Lewin, Adelle Abramovitz, Larry V. Pearce, Peter M. Blumberg, and Jeewoo Lee*

    Bioorganic & Medicinal Chemistry Letters, 2016, 26(15), 3603-3607. (SCIE, IF 2.486, ’15)

    Link
  • 63
    A novel pyrazole derivative protects from ovariectomy-induced osteoporosis through the inhibition of NADPH oxidase

    Jung Hee Joo, Jeong-Eun Huh, Jee Hyun Lee, Doo Ri Park, Yoonji Lee, Seul Gee Lee, Sun Choi, Hwa Jeong Lee, Seong-Won Song, Yongmi Jeong, Ja-Il Goo, Yongseok Choi, Hye Kyung Baek, Sun Shin Yi, Soo Jin Park, Ji Eun Lee, Sae Kwang Ku, Won Jae Lee, Kee-In Lee*, Soo Young Lee*, and Yun Soo Bae*

    Scientific Reports, 2016, 6(1), 22389. (SCIE, IF 5.228, ’15)

    Link
  • 62
    Polymodal Transient Receptor Potential Vanilloid Type 1 Nocisensor: Structure, Modulators, and Therapeutic Applications

    Minghua Cui, Vijayakumar Gosu, Shaherin Basith, Sunhye Hong, and Sun Choi*

    Advances in Protein Chemistry and Structural Biology, 2016, 104, 81–125. (SCIE, IF 3.783, ’18)

    Link
  • 61
    2-Sulfonamidopyridine C-region analogs of 2-(3-fluoro-4-methylsulfonamidophenyl)propanamides as potent TRPV1 antagonists

    Jihyae Ann, Yooran Ki, Suyoung Yoon, Myeong Seop Kim, Jung-Un Lee, Changhoon Kim, Sunho Lee, Aeran Jung, Jisoo Baek, Sunhye Hong, Sun Choi, Larry V. Pearce, Timothy E. Esch, Noe A. Turcios, Nancy E. Lewin, Adebowale E. Ogunjirin, Brienna K. A. Herold, Anna K. McCall, Peter M. Blumberg, and Jeewoo Lee*

    Bioorganic & Medicinal Chemistry, 2016, 24(6), 1231-1240. (SCIE, IF 2.923, ’15)

    Link
  • 60
    Structure activity relationships of benzyl C-region analogs of 2-(3-fluoro-4-methylsulfonamidophenyl)propanamides as potent TRPV1 antagonists

    Jihyae Ann, Aeran Jung, Mi-Yeon Kim, Hyuk-Min Kim, HyungChul Ryu, Sunjoo Kim, DongWook Kang, Sunhye Hong, Minghua Cui, Sun Choi, Peter M. Blumberg, Robert Frank-Foltyn, Gregor Bahrenberg, Hannelore Stockhausen, Thomas Christoph, and Jeewoo Lee*

    Bioorganic & Medicinal Chemistry, 2015, 23(21), 6844-6854. (SCIE, IF 2.793, ’14)

    Link
  • 59
    5-Lipoxygenase inhibitors suppress RANKL-induced osteoclast formation via NFATc1 expression

    Ju-Hee Kang, Zheng Ting, Mi-ran Moon, Jung-Seon Sim, Jung-Min Lee, Kyung-Eun Doh, Sunhye Hong, Minghua Cui, Sun Choi, Hyeun Wook Chang, Hea-Young Park Choo*, and Mijung Yim*

    Bioorganic & Medicinal Chemistry, 2015, 23(21), 7069-7078. (SCIE, IF 2.793, ’14)

    Link
  • 58
    The Cell Shape-determining Csd6 Protein from Helicobacter pylori Constitutes a New Family of L,D-Carboxypeptidase

    Hyoun Sook Kim, Ha Na Im, Doo Ri An, Ji Young Yoon, Jun Young Jang, Shahriar Mobashery, Dusan Hesek, Mijoon Lee, Jakyung Yoo, Minghua Cui, Sun Choi, Cheolhee Kim, Nam Ki Lee, Soon-Jong Kim, Jin Young Kim, Geul Bang, Byung Woo Han, Byung Il Lee, Hye Jin Yoon, and Se Won Suh*

    Journal of Biological Chemistry, 2015, 290(41), 25103-25117. (SCIE, IF 4.573, ’14)

    Link
top